pH Adjusting Database
Last Review: August 2005
For all the reasons cited above, many times a formulation may already contain one of these agents to achieve a desirable pH. In all cases, before finishing up preparing a formulation that contains water, the pharmacist must check the pH and adjust it, if needed. Generally, because of easy incorporation, freshly prepared solutions of these agents can be used to adjust pH in such formulations.
The USP XXVIII/NF 23 specifically lists 14 acidifying agents and 9 alkalizing agents although other agents can also be used for their pH-altering effect.