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Loss on Drying

Last Review: June 2005

The description of the "loss on drying" in a chemical analysis should fall within the allowable range described in that document. Therefore, upon receiving a chemical, the pharmacist must note if the value for loss on drying falls within the allowable specification; if it doesn't, the pharmacist must return the chemical to the manufacturer.


Description Limit (min- max) Result
Loss on drying up to 0.5% 0.04%

In this case, the limits in the assay value are established by the USP and the result falls within the allowable range. Therefore, no correction is required.