Loss on Drying
Last Review: June 2005
The description of the "loss on drying" in a chemical analysis should fall within the allowable range described in that document. Therefore, upon receiving a chemical, the pharmacist must note if the value for loss on drying falls within the allowable specification; if it doesn't, the pharmacist must return the chemical to the manufacturer.
Example:
| DEXCHLORPHENIRAMINE MALEATE, USP | ||
|---|---|---|
| Description | Limit (min- max) | Result |
| Loss on drying | up to 0.5% | 0.04% |
In this case, the limits in the assay value are established by the USP and the result falls within the allowable range. Therefore, no correction is required.
