Last Review: March 2006
Although most liquid pharmaceuticals are aqueous, a drug must often be formulated in a nonaqueous vehicle. For example, the drug may have limited water solubility, or it may not be stable in an aqueous vehicle. Drugs formulated in oil vehicles may have different release characteristics that result in a different onset and duration of action. Nonaqueous vehicles are routinely used for oral, topical, rectal, otic, nasal (limited), and parenteral formulations.
This database describes several oleaginous vehicles used in pharmaceutical compounding.