Compounding This Week Newsletter from www.CompoundingToday.com
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June 3, 2011 Volume 8, Issue 22
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IACP Annual Meeting and Compounders on Capitol Hill - June 11-14, 2011

IJPC Journal Binders

 
Nasoneb - The Drug Delivery Solution for the Sinonasal Region
 
Loyd V. Allen, Jr., Ph.d., R.Ph  Letter from the Editor
Loyd V. Allen, Jr., Ph.D., R.Ph.


Editorial: Disappointment, Disillusionment, Disgust!

This editorial is not directed to those that are on the right path and are doing a great job in the government and those elected to Congress, etc�.only to those that have lost their way.

Many are disappointed at the actions of our political leaders who seem to be so intent on running for re-election that they may not be voting their conscience, values, etc. They would rather criticize others that submit solutions to problems rather than develop their own. Many have "sold out" to lobbyists for personal gain. (How can a $100,000 a year person leave a job, go to Washington, and become a millionaire on the salary of a Congressperson?)

Many are disillusioned because, living in the greatest country in the world, we see an erosion of the values upon which this country was built. Those values, which we enjoy and the world envies, were the foundation for our current success. Many have developed the attitude that why work when the government will pay you and you can stay home. There is one local story of a lady who had been on welfare all her life except for one year. When interviewed about it, she said "that was the worst year of my life when I had to go to work"!

Many are disgusted at the waste and dishonesty that has permeated our government, including many of our elected officials. The lack of truthfulness, evasive responses to questions, and blame-shifting are now commonplace. The lack of enforcement of select laws on the books is appalling! Too many will defend their party or certain individuals even when the facts show otherwise. Also, how many times do you hear "facts" that are distorted and untrue? How can they say "The fact is�" when they are only parroting something else they have heard and will not or cannot provide documentation.

As citizens, we deserve better�all those that have died to make this country free and great deserve better�our children and grandchildren deserve better�as pharmacists, our patients deserve better�as taxpayers, we deserve an accounting of our tax dollars, the elimination of departments of the government that do not serve a suitable purpose, and an accounting of expenditures, including salaries, benefits, etc. Budget reductions must be discussed. The government must have a "balanced budget." They can only spend one dollar for every dollar they receive!

It appears that we are morphing into a centralized power government, the same as many other countries (many of which are in upheaval) and are "developing" countries. The U.S. is a "developed" country that is built on hard work, honesty, family values, etc. We do have problems, but they cannot be resolved by governmental programs and forcing our jobs overseas. Our practice of pharmacy has changed in the last 50 years, but the "rate of change" may come at warp speed unless we all become active. Support IACP and attend the Compounders on Capitol Hill meeting June 11-14 in Washington and let your voice be heard by your elected representatives!


Loyd V. Allen, Jr., Ph.D., R.Ph.
Editor-in-Chief

 
Other News

Is the High Price of Drugs Justifiable?
PHARMA companies are excited to tout the benefits of their newest drugs but seem far less willing to let the public know the price of the product.

  1. Optimer Pharmaceuticals announced that its new drug to treat diarrhea caused by the bacterium Clostridium difficile would cost $2,800, about twice as much as the existing approved drug.
  2. Vertex Pharmaceuticals provided a lot of information about how generous the company was going to be in helping customers with their insurance copayments but was silent about how much the drug would actually cost-$49,000.
  3. Merck's $1,100-a-week price of its new hepatitis C drug, Victrelis, is another example.

Some physicians are becoming frustrated trying to find documented information, outside of news reports, on the price of the new hepatitis C drugs. It is really remarkable that patients and physicians often don't know how much treatments or tests cost.
http://prescriptions.blogs.nytimes.com/2011/05/31/the-hidden-price-of-drugs/

Sanofi, Genzyme and 4,500 Employees
After Sanofi closed its $20 billion deal to buy Genzyme. CEO Chris Viehbacher made it clear that the biotech company would remain a standalone entity. Now, he announced that only a scaled-down version of Genzyme will remain semi-independent as Sanofi absorbs the rest of the company into its system. What isn't clear is whether the new corporate structure will trigger layoffs affecting Genzyme's 4,500 Boston employees (10,000 worldwide). In every significant buyout of the past several years, these mergers have been the catalyst for major job cuts.
http://www.fiercebiotech.com/story/sanofi-spurs-layoff-fears-genzyme-restructuring-plans/2011-06-01

Rising Violence in Hospitals
Hospitals are no longer immune to America's increasing violence. Hospitals were at one time much like churches and schools and were considered somewhat isolated from violence. Unfortunately, that's not the case anymore.

Dr. Dmitriy Nikitin, an Orlando surgeon, was murdered last week; shot by a disgruntled patient. More than ever, patients are targeting doctors. It seems we live in an era where, if I have a problem, it's not my fault. The scenario occurred when Nelson Flecha, a 53-year-old man whom police described as a disgruntled patient, shot the 41-year-old transplant surgeon in Florida Hospital's parking garage and then killed himself.

American hospitals are experiencing more violence on their grounds and inside their corridors than ever before; last year, the Joint Commission reported that there have been 110 assaults, rapes, or homicides at hospitals and healthcare facilities since 2007.
http://www.orlandosentinel.com/health/os-hospital-security-20110531,0,6124785.story

No More Free International Trips for Doctors from AstraZeneca
AstraZeneca is scrapping payments for doctors to attend international medical congresses. This follows increased scrutiny of the $850 billion-a-year industry's potentially undue influence on prescribers and could put pressure on other companies to follow suit. European and other international congresses are often held on topics like cancer, heart disease, and diabetes. Typically, planeloads of specialist physicians are flown in at Big Pharma's expense to attend.

The company has decided that it will focus educational efforts on local educational opportunities for healthcare professionals. This decision comes at a time of unprecedented regulatory pressure on the drugs industry, which in the past five years has paid $15 billion penalties to the U.S. government alone for alleged violations of laws and regulations. Also impacting the decision may have been a wave of investigations under the U.S. Foreign Corrupt Practices Act (FCPA) and the introduction of a new bribery act in Britain. AstraZeneca is actually being investigated by the U.S. Department of Justice and the Securities and Exchange Commission in connection with the FCPA.
http://www.reuters.com/article/2011/05/27/astrazeneca-junkets-idUSLDE74P1YI20110527

North America's PHARMA Driving Up Costs
North America's (NA) PHARMA companies are turning to international markets for growth; they're scouting Central Europe, Eastern Europe, Turkey, and the Middle East for potential generics deals. This is likely to push prices upward on the world market.

It has been that most Central European PHARMA deals went to a European drugmaker or an Indian company; now, NA PHARMA is swooping in. As an example, Canadian drugmaker Valeant Pharmaceuticals bought out Lithuania's AB Sanitas, and U.S.-based Watson Pharmaceuticals purchased Greece's Specifar.

In these deals, the entire bidding pool was dominated by North American companies. The problem is there aren't that many midsized generics firms to go around in those regions. There's now a "scarcity premium," which will increase as consolidation continues.
http://online.wsj.com/article/BT-CO-20110527-708452.html

France to Stop Paying for Pfizer's Champix
France will no longer pay for Pfizer's stop-smoking drug Champix. The treatment will be pulled from the government formulary of medications eligible for reimbursement because of ongoing controversy about its potential side effects, Health Minister Xavier Bertrand said. "Questions have been raised about Champix, so I've decided it will no longer be covered by (state) health insurance," said Bertrand.
http://www.forexyard.com/en/news/France-pulls-subsidy-for-Pfizer-stop-smoking-drug-2011-05-31T105429Z

Bayer Moving Drug Production from California to Germany
Bayer has announced it will shut down production of a key drug in California, a move that would claim some 540 jobs by 2013. The company is confirming that production will go to Boehringer Ingelheim in a move designed to control costs as competitive pressures for its Betaferon multiple sclerosis treatment ratchet up. Boehringer is a German company, the biggest in that country next to Bayer. Bayer says. "It is important for us that we can offer the product from a single source."
http://www.reuters.com/article/2011/05/31/bayer-boehringer-idUSLDE74U0WZ20110531

 
Did You Know...

�that there is a study published in Pharmaceutical Research (May 5, 2011) that evaluated the use of thermal ink-jetting (TIJ) as a method for dosing drugs onto oral films? An HP printer cartridge was modified so that aqueous drug solutions replaced the ink. The work involved viscosity and surface tension measurements as they affect the amount of drug deposited. Their conclusion was that the TIJ method offers a rapid method for extemporaneous preparation of personalized-dose medicines.

 
Compounding Tip of the Week

Be Careful What Brand of Tablets You are Using in Your Preparations
When preparing a mercaptopurine oral suspension using mercaptopurine 50-mg tablets, Mylan brand tablets make a creamier/smoother oral suspension, whereas the Roxanne brand creates a globby, gritty suspension that looks like mucous with sand. Note: This tip of the week was provided by Lisa D. Ashworth, BS, RPh, Children's Medical Center Dallas, Dallas, TX 75235.

 
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Newer model (one station , automated) preferred. Aluminum/teflon seal strip. Shipping paid for right price. Contact Rmossor@tagaseptic.com.

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