Largest U.S. Hospital Drug Shortage in Decades
Many patients are being turned away for potentially life-saving treatments in what may be the largest U.S. hospital drug shortage in over two decades. According to an editorial of the NEJM (August 2010), limited manufacturing, lagging production time, and lack of profits from these drugs are contributing to the shortage. Some companies state that the production cost outweighs the profits, and many firms would rather produce cheaper generic drugs.
Doctors at local hospitals are frustrated and many times they're not even informed of the shortage, according to survey results released in September by the Institute for Safe Medication Practices. Of those surveyed, 85 percent said they were given little to no information on how long the shortages would last.
This is causing hospitals to spend a great deal of physician and pharmacy time developing priority procedures to allocate available drug, as well as to scour suppliers for drug shipments.
http://abcnews.go.com/Health/CancerPreventionAndTreatment/largest-hospital-drug-shortage-decades/story?id=12452389&page=1
(Editors Note: Would it not be better to have uniform compounding monographs in the USP so compounding pharmacists can fill the need with preparations of the same formulation as those that are manufactured during the time of shortage of a drug?)
Sodium Bicarbonate and Dexamethasone Recalled by American Regent
American Regent has announced a recall of all unexpired 50-mL vials of 7.5% or 8.4% sodium bicarbonate injection and seven lots of 4-mg/mL dexamethasone sodium phosphate injection in 30-mL vials.
The company states that some of the vials contain particulates or have the potential to form particulates before the expiration date.
http://www.ashp.org/import/news/HealthSystemPharmacyNews/newsarticle.aspx?id=3453
A Push to Ease Prescription Drug Shortages
A proposal to ease restrictions on imports of medication from abroad was announced at a news conference to voice concern about a growing shortage of prescription drugs, including morphine and cisplatin, a widely used cancer drug.
According to the announcement, 150 drugs are now considered in short supply in the U.S.-twice as many as five years ago. As a result, there are plans to introduce legislation to speed up the availability of substitutes, including comparable drugs from other countries.
Shortages have been blamed, in part, on production problems as well as decisions by manufacturers to stop making inexpensive generic drugs. Also, a California plant that manufactures cisplatin was shut down by federal authorities earlier this year because of concerns about bacterial contamination.
The proposal would ease restrictions on importing foreign drugs from countries such as Canada, especially when medications are in short supply here. Foreign drugs cannot be imported legally into the U.S., although the FDA can allow exceptions in rare cases.
http://www.startribune.com/lifestyle/health/112639829.html?elr=KArks8c7PaP3iUMEaPc:E7_ec7PaP3iUiD3aPc:_Yyc:aULPQL7PQLanchO7DiUr
(Editors Note: As stated above, would it not be better to have uniform compounding monographs in the USP so compounding pharmacists can fill the need with preparations of the same formulation as those that are manufactured during the time of shortage of a drug?)
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