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May 28, 2010 Volume 7, Issue 22
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Loyd V. Allen, Jr., Ph.d., R.Ph  Letter from the Editor
Loyd V. Allen, Jr., Ph.D., R.Ph.


Editorial: Spring Cleaning

Well, it's that time of year again; with warm weather and the urge to get rid of the "confines" of winter, we tend to want to "lighten our load." This can involve spring cleaning, going on a diet, starting to exercise, or any of a number of things to burn up some stored energy from the wild winter we just had.

Spring cleaning often begins with a serious attempt to clean out closets, garages, and other places to help make our lives more efficient and manageable. However, that old basketball goal in the corner is still good and I can fix it up, paint it, put on a new net, and hang it on the garage and that way I will get some exercise (Right?). So, for now, let's leave it there. Oh, and those tools that are broken, I also can fix those as soon as I have time. That old bicycle against the wall only needs two tires and a new chain�I think I can get that working again and then I can ride it for exercise. Oh yes, and that rototiller just needs some work on the carburetor, and it will be good as new and I can start up my garden again. I was going to give that box of books to Goodwill, but I'm not sure I've read them all yet�in fact, I don't recall reading any of them�so maybe I should do that before I give them away.

Well, it's lunchtime and I'd better quit for today. It really feels good doing Spring Cleaning every year!

Loyd V. Allen, Jr., PhD, RPh
Editor-in-Chief

 
Other News

Doctors First, Google Second as Source of Health Information
According to a national survey, Americans rely heavily on Google searches as a source of healthcare information. The survey, conducted in April 2010, found 22 percent of respondents consider Google searches "influential" in seeking health information. First in the ranking was doctors at 44 percent in reported influence and was named more than twice as often as nurses, pharmacists, advocacy groups, and friends or family members.

The poll also asked which sources they trust; health advocacy groups emerged as a particularly trusted source of online health information. Of this, 71 percent judged Web content of such groups "somewhat reliable" or "extremely reliable."

Younger respondents were much less likely to see pharmacists as reliable sources of information, perhaps reflecting the more impersonal relationship they have with chain pharmacists compared to their parent's long-standing reliance on independent pharmacies over the years.
http://pharmalive.com/news/index.cfm?articleID=704905&categoryid=43

Kids' Use of Chronic Prescription Medications Rises 5%
More than one-in-four children take medications to treat ongoing health conditions. In growing numbers in America, children are adding a dose of medicine to their daily routine. In 2009, prescription spending growth increased 10.8 percent, driven by a 5 percent increase in drug utilization and higher medication costs, according to the Medco 2010 Drug Trend Report. The growth in prescription drug use among children was nearly four times higher than the rise seen in the overall population.

A corresponding analysis of pediatric medication use found that in 2009, more than one in four insured children in the U.S. and nearly 30 percent of adolescents (10- to 19-year olds) took at least one prescription medication to treat a chronic condition; the most substantial increases were seen in the use of antipsychotic, diabetes, and asthma drugs over the past nine years.
http://pharmalive.com/news/index.cfm?articleID=705668&categoryid=43

FDA Warned Dozens of Drug Factories Since 2009
About 43 drug companies have received government warnings in recent months for failing to correct improper manufacturing practices that may have exposed patients to health risks. The warning letters, issued since January 2009, reflect only some of the most serious manufacturing violations the FDA found during facility inspections. During 2002 to 2006, for example, more than half of inspections at domestic drug plants and 62 percent at foreign plants supplying the U.S. had violations that didn't prompt warning letters but were classified as requiring correction.
http://www.usatoday.com/news/health/2010-05-26-drug-factories-warned_N.htm

Perrigo Plant Released Drugs Contaminated With Metal
U.S. regulators said Perrigo failed to protect consumers from ibuprofen tablets contaminated with metal shavings four years after the company recalled similarly tainted acetaminophen products.

The world's largest maker of nonprescription, store-branded drugs, was forced to pull the ibuprofen from the market after the tablets were released by its Allegan, Michigan, plant. The company failed to thoroughly investigate why some tablets were the wrong size and didn't inspect packaging equipment between batches, the FDA said.

The warning follows Perrigo's 2006 recall of 11 million bottles of acetaminophen products containing pieces of wire as long as 8 millimeters (0.32 inches). The FDA ordered the company to fix its quality-control issues or face product seizure, injunction, or a ban on exports or new product approvals.
http://www.businessweek.com/news/2010-05-25/perrigo-plant-released-drugs-contaminated-with-metal-update2-.html

Johnson & Johnson May Face Criminal Charges for Pattern of Violations
Government officials have said they are considering criminal charges against Johnson & Johnson, resulting from last month's recall of Tylenol and other popular OTC children's medicines. Johnson & Johnson insists it has taken dramatic steps to clean up the plants where the recalled products are made. Meanwhile, the FDA says it has referred the matter to its criminal division for consideration.

Last year, when the situation with Motrin IB caplets that were not dissolving properly came up, McNeil Consumer Healthcare (a division of J&J), hired contractors to buy the products under orders not to mention the term "recall." When the FDA discovered what was going on (as one of the contractors accidentally dropped an instruction sheet on the floor of a store), McNeil announced a recall of roughly 88,000 packages of the product. Since last year, there have been four recalls of McNeil products; this includes an April 30 recall of 136 million bottles of infant and children's Tylenol, Motrin, Benadryl, and Zyrtec.
http://www.nytimes.com/2010/05/28/business/28drug.html?src=busln

 
Website/Book Review

InteractionsGuideTM
Drug-Herb and Drug-Nutrient Interactions Web Application
www.MedicineWorks.com

This is a very good evidence-based website that is well-designed and easy to navigate. It is an innovative web-based application that provides access to considerable content on the landmark publication Herb, Nutrient and Drug Interactions: Clinical Implications and Therapeutic Strategies. This site contains very powerful functions for access, search, and analysis, providing instant access to evidence-based information and evaluation of herbs and nutritional supplements. The site contains seventy comprehensive monographs of herb-drug and nutrient-drug interactions; each monograph features summary tables and concise, practical but detailed information. The monographs contain very detailed and referenced information that is well-organized and easy-to-read. The innovative evaluation system and very unique "icons" differentiate interactions, qualify evidence, and assess clinical significance. The website also provides "bundles" as an added option.

 
Did You Know...

... that Memorial Day is observed the last Monday of May? Formerly, it was known as Decoration Day and commemorates U.S. men and women who died while in the military service. It was first enacted following the American Civil War and was expanded after World War I. Many observe this holiday by visiting cemeteries and memorials. A national moment of remembrance takes place at 3 p.m. local time. Another tradition is to fly the flag of the United States at half-staff from dawn until noon local time. Volunteers often place American flags on each grave site at National Cemeteries. Many visit local cemeteries and place flowers and/or flags on the graves of loved ones. It is also considered as the "official" beginning of summer.

 
Compounding Tip of the Week

Memorial Day

Memorial Day is a time to spend with family and friends; participate in picnics, barbecues, family gatherings, and sporting events.

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