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Compounding This Week Newsletter from www.CompoundingToday.com
Our Compounding Knowledge, Your Peace of Mind
August 12, 2022  |  Volume 19  |  Issue 32
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Loyd V. Allen, Jr., Ph.d., R.Ph Letter from the Editor
Cosmetics for Special Populations and for Use as Compounding Vehicles

Part 9: SPF Values for Sunscreens

We are completing our series on "Compounding Cosmetics for Special Populations and for Use as Compounding Vehicles" by looking at sunscreen ingredients, their concentrations, and their effective wavelength ranges.

Sunscreen Ingredients in Cosmetics

Sunscreen Protection Factor (SPF) is a measure of how much solar energy (UV radiation) is required to produce sunburn on protected skin (i.e., in the presence of sunscreen) relative to the amount of solar energy required to produce sunburn on unprotected skin. As the SPF value increases, sunburn protection increases.

In addition to solar intensity, there are a number of other factors that influence the amount of solar energy that a consumer is exposed to:

  • skin type
  • amount of sunscreen applied
  • reapplication frequency

The FDA regulates sunscreens to ensure they meet safety and effectiveness standards. To improve the quality, safety, and effectiveness of sunscreens, the FDA posted a proposed order on September 24, 2021 that describes updated proposed requirements for sunscreens. Given the recognized public health benefits of sunscreen use, Americans should continue to use sunscreen with other sun protective measures as this important effort moves forward. The following table provides a list of sunscreen ingredients, their concentrations, and their effective wavelength ranges when used in sunscreen products.

Names, Concentrations, and Wavelength Ranges of Ingredients Used to Increase the SPF of Products.
Name Concentration % Absorbancea
Aminobenzoic acid ≤15 UVB
Avobenzone 2-3 UVA I
Cinoxate ≤3 UVB
Dixoybenzone ≤3 UVB, UVA II
Homosalate ≤15 UVB
Menthyl anthranilate ≤5 UVA II
Octinoxate ≤7.5 UVB
Octisalate ≤5 UVB
Octocrylene ≤10 UVB
Oxybenzone ≤6 UVB, UVA II
Padimate O ≤8 UVB
Phenylbenzimidazole sulfonic acid ≤4 UVB
Sulisobenzone ≤10 UVB, UVA II
Titanium dioxide 2-25 Physical
Trolamine salicylate ≤12 UVB
Zinc oxide 2-20 Physical

aUVB = 290-320 nm; UVA = 320-400 nm; UVA I = 340-400 nm; UVA II (also called near UVA) = 320-340 nm.

Test your knowledge on sunscreens at:
FDA sunscreens quiz


Loyd V. Allen, Jr., PhD, RPh
Editor-in-Chief

International Journal of Pharmaceutical Compounding
Remington: The Science and Practice of Pharmacy Twenty-second edition

 

New Dosage Form Coming

Microneedle Arrays (MNAs), a new generation of transformative skin-mediated delivery systems, will soon be introduced as a new pharmaceutical dosage form,

Read about Microneedle Arrays and how to become involved with them in the upcoming issues of the International Journal of Pharmaceutical Compounding.

If not a current subscriber, subscribe online now to IJPC to see where compounding has new potential and opportunities. Call Deb at 800-757-4572 ext 1, or email at
IJPC-Subscriptions@IJPC.com

In the next three issues of IJPC, microneedle arrays will be discussed along with their potential use in compounding.

Sep/Oct 2022   Compounding with Microneedle Arrays, Part 1: Introduction and Overview
Nov/Dec 2022   Compounding with Microneedle Arrays, Part 2: Preparation, Compounding, and Recent Studies
Jan/Feb 2023   Compounding with Microneedle Arrays, Part 3: Preparation of Microneedle Array Blanks and Literature Examples

 

Did You Know (On Truth) ...

...the following?

"Truth is the foundation of all knowledge and the cement of all societies." (John Dryden)

"Some persons have tact, others tell the truth." (Anon)

 

Thought of the Week (On Truth)

"Truth is always the strongest argument." (Sophocles)

Teacher: "What do the philosophers call 'truth'?"
Student: "When one fisherman calls another fisherman a liar." (Anon)

 

Get a Sample of IJPC

Get a free digital sample issue of the International Journal of Pharmaceutical Compounding - the only journal solely dedicated to compounding - at IJPC.com/FreeSample

Like what you see? Subscribe today to receive the latest digital issue and be in time to get the September/October 2022 print issue delivered to your door!

 

From Out of the Past

Bag of Trix
Here's the one
That clix
With chix
     Burma-Shave

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