Book Review

Estrogens and Progestogens in Clinical Practice

Ian S. Fraser Jansen RPS, Lobo RA, et al., eds.
Churchill Livingstone

Not recommended for patients but excellent for healthcare professionals who need a comprehensive source of information on estrogens and progestogens

This reference text provides a comprehensive analysis of the physiologic, pathophysiologic, pharmacologic, and therapeutic effects of bioidentical estrogens and progestogens at molecular, cellular, and tissue levels. The text is well-referenced, and each chapter concludes with a comprehensive bibliography. The index is comprehensive, wellstructured, and easy to use. Estrogens and Progestogens in Clinical Practice is a valuable reference for researchers, physicians, and pharmacists involved in any field of hormone replacement therapy.

The book is divided into sections that address the following topics:

  • An overview of the discovery of steroid hormones and their development as therapeutic agents
  • The biochemical effects of the steroids (the structure, function, and metabolic effects of bioidentical and synthetic hormones and antihormones)
  • Bioidentical hormone replacement therapy and its effects
  • A laboratory assessment of hormones and imaging of the reproductive tract
  • The pathophysiology of gynecologic conditions such as menstrual disorders, cancer of the reproductive system, premenstrual syndrome, endometriosis, polycystic ovary syndrome, and benign breast disease and the therapies used to treat those disorders
  • Menopause and the benefits and risks of hormone replacement therapy ¦ The metabolic actions and long-term side effects of steroid use
  • The physiologic and psychologic effects of estrogens and progestogens on cancers, carbohydrate metabolism, plasma lipids and lipoproteins, the immune system, and the central nervous system

Estrogens and Progestogens in Clinical Practice is an excellent reference for compounding pharmacists who specialize in bioidentical natural hormone replacement. For those interested in current information on that topic, this book could be difficult to put down.

Reviewed By:  James Paoletti, RPh
In:  Sep/Oct 2001